{"product_id":"dsip-pen-refill","title":"DSIP Pen Refill","description":"\u003cp\u003e\u003cstrong\u003eDSIP — The Sleep Peptide\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eStudied for delta-wave sleep activity\u003c\/li\u003e\n\u003cli\u003eNonapeptide that crosses the blood–brain barrier\u003c\/li\u003e\n\u003cli\u003eAlso investigated in stress and analgesia research\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch2\u003eOverview\u003c\/h2\u003e\n\u003cp\u003eDSIP pen refill cartridge, supplied ready to insert into a peptide pen. Available in 5mg.\u003c\/p\u003e\n\u003cp\u003eEach cartridge is reconstituted and filled individually at the point of order — we never hold pre-reconstituted stock on a shelf. Made-to-order items are dispatched within 48 hours.\u003c\/p\u003e\n\n\u003ch2\u003eKey Specifications\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eProduct format:\u003c\/strong\u003e Pre-filled pen cartridge, made to order\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAvailable sizes:\u003c\/strong\u003e 5mg\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSource compound:\u003c\/strong\u003e DSIP — \u003ca href=\"\/products\/dsip\"\u003ealso available as a lyophilised powder vial\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAlso available as:\u003c\/strong\u003e \u003ca href=\"\/products\/dsip-nasal-spray\"\u003eDSIP nasal spray\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSequence:\u003c\/strong\u003e Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu (WAGGDASGE) — linear nonapeptide\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePurity:\u003c\/strong\u003e Verified by HPLC on every batch — the measured figure for your lot is published on its certificate of analysis\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePreparation:\u003c\/strong\u003e Reconstituted and filled to order, never pre-mixed\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStorage:\u003c\/strong\u003e Refrigerate on arrival; keep away from light\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDispatch:\u003c\/strong\u003e Within 48 hours (made to order)\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eIntended use:\u003c\/strong\u003e Laboratory research use only\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch2\u003eResearch Focus\u003c\/h2\u003e\n\u003cp\u003eDSIP was isolated in 1977 from the cerebral venous blood of rabbits undergoing induced slow-wave sleep, and takes its name from the delta-wave EEG activity observed in those experiments. Early human work examined its influence on disturbed sleep, with published studies reporting shorter sleep onset latency and improved sleep efficiency.\u003c\/p\u003e\n\u003cp\u003eResearch interest has since extended beyond sleep, into stress-axis and corticotropin regulation, thermoregulation, analgesia, opioid withdrawal models and antioxidant activity — which is why the literature often describes DSIP as multifunctional rather than sleep-specific.\u003c\/p\u003e\n\u003cp\u003eIt is worth being clear about the state of the evidence: despite the name, DSIP's status as an endogenous sleep factor remains unresolved. No corresponding gene, precursor protein or receptor has been identified, and findings across studies have been inconsistent — a 2006 review in the \u003cem\u003eJournal of Neurochemistry\u003c\/em\u003e characterised it as a still-unresolved riddle. DSIP remains an active subject of laboratory investigation rather than a settled one.\u003c\/p\u003e\n\n\u003ch2\u003eTesting \u0026amp; Certificates of Analysis\u003c\/h2\u003e\n\u003cp\u003eCartridges are filled from the same independently tested material as our powder vials — HPLC purity and mass-spectrometry identity, certified per batch and published on our \u003ca href=\"\/pages\/lab-results\"\u003elab results page\u003c\/a\u003e.\u003c\/p\u003e\n\n\u003ch2\u003eReturns\u003c\/h2\u003e\n\u003cp\u003eMade-to-order items are prepared individually for you and are exempt from the 14-day cancellation right under the Consumer Contracts Regulations 2013. They cannot be returned or refunded unless faulty, damaged or not as described. See our \u003ca href=\"\/policies\/refund-policy\"\u003erefund policy\u003c\/a\u003e.\u003c\/p\u003e\n\n\u003cp\u003e\u003cstrong\u003eFor laboratory research use only.\u003c\/strong\u003e All products sold by PepSource are strictly for laboratory research purposes and are not intended for human or veterinary consumption. No dosing, administration or physiological guidance is provided.\u003c\/p\u003e","brand":"PEP SOURCE","offers":[{"title":"5mg","offer_id":53882832912712,"sku":null,"price":23.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0974\/5593\/1720\/files\/5a64486d9586ac1716bed874e1b01020d6bc23ce6ec829e6a3daa118a8908402_b43626a8-b9c2-4946-b575-e6068a22561b.jpg?v=1787354844","url":"https:\/\/pepsource.co.uk\/products\/dsip-pen-refill","provider":"PepSource","version":"1.0","type":"link"}