{"product_id":"dsip","title":"DSIP","description":"\u003cp\u003e\u003cstrong\u003eDSIP — The Sleep Peptide\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eStudied for delta-wave sleep activity\u003c\/li\u003e\n\u003cli\u003eNonapeptide that crosses the blood–brain barrier\u003c\/li\u003e\n\u003cli\u003eAlso investigated in stress and analgesia research\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch2\u003eOverview\u003c\/h2\u003e\n\u003cp\u003eDSIP (delta sleep-inducing peptide) is a nonapeptide first isolated in 1977 from the cerebral venous blood of rabbits undergoing induced slow-wave sleep. It carries the sequence Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu and is supplied as a lyophilised powder in a sealed vial for laboratory and in-vitro research.\u003c\/p\u003e\n\u003cp\u003ePepSource supplies DSIP in 5mg vials. Every batch is independently third-party tested for HPLC purity and mass-spectrometry identity, and the certificate of analysis for the batch you receive is published on our \u003ca href=\"\/pages\/lab-results\"\u003elab results page\u003c\/a\u003e.\u003c\/p\u003e\n\n\u003ch2\u003eKey Specifications\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eProduct format:\u003c\/strong\u003e Lyophilised powder, sealed vial\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAvailable sizes:\u003c\/strong\u003e 5mg vial\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSequence:\u003c\/strong\u003e Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu (WAGGDASGE) — linear nonapeptide, no disulfide bonds\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMolecular formula:\u003c\/strong\u003e C\u003csub\u003e35\u003c\/sub\u003eH\u003csub\u003e48\u003c\/sub\u003eN\u003csub\u003e10\u003c\/sub\u003eO\u003csub\u003e15\u003c\/sub\u003e — molecular weight approximately 848.8 Da\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCAS number:\u003c\/strong\u003e 62568-57-4\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePurity:\u003c\/strong\u003e Verified by HPLC on every batch — the measured figure for your lot is published on its certificate of analysis\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStorage:\u003c\/strong\u003e Store sealed vials cool, dry and away from light; freeze for long-term storage\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eReconstitution:\u003c\/strong\u003e Bacteriostatic water — see our \u003ca href=\"\/pages\/reconstitution-guide\"\u003ereconstitution guide\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eIntended use:\u003c\/strong\u003e Laboratory research use only\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch2\u003eResearch Focus\u003c\/h2\u003e\n\u003cp\u003eDSIP takes its name from the delta-wave EEG activity observed after infusion in the original rabbit experiments. Early human work examined its influence on disturbed sleep, with published studies reporting shorter sleep onset latency and improved sleep efficiency, including effects measured on the following night rather than only immediately after administration.\u003c\/p\u003e\n\u003cp\u003eResearch interest has since extended well beyond sleep. Published work has examined DSIP in relation to stress-axis and corticotropin regulation, thermoregulation, analgesia, opioid withdrawal models and antioxidant activity — which is why the literature often describes it as multifunctional rather than sleep-specific.\u003c\/p\u003e\n\u003cp\u003eIt is worth being clear about the state of the evidence: despite the name, DSIP's status as an endogenous sleep factor remains unresolved. No corresponding gene, precursor protein or receptor has been identified, and findings across studies have been inconsistent — a 2006 review in the \u003cem\u003eJournal of Neurochemistry\u003c\/em\u003e characterised it as a still-unresolved riddle. DSIP remains an active subject of laboratory investigation rather than a settled one.\u003c\/p\u003e\n\n\u003ch2\u003eTesting \u0026amp; Certificates of Analysis\u003c\/h2\u003e\n\u003cp\u003eEach batch is tested by an independent analytical laboratory for HPLC purity and mass-spectrometry identity before release. Certificates are published per batch and searchable by lot code on our \u003ca href=\"\/pages\/lab-results\"\u003elab results page\u003c\/a\u003e — you can verify the exact vial you were sent.\u003c\/p\u003e\n\n\u003cp\u003e\u003cstrong\u003eFor laboratory research use only.\u003c\/strong\u003e All products sold by PepSource are strictly for laboratory research purposes and are not intended for human or veterinary consumption. No dosing, administration or physiological guidance is provided.\u003c\/p\u003e","brand":"PEP SOURCE","offers":[{"title":"5mg","offer_id":53882685358408,"sku":"DS5","price":18.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0974\/5593\/1720\/files\/DSIP_5_mg.png?v=1787350361","url":"https:\/\/pepsource.co.uk\/products\/dsip","provider":"PepSource","version":"1.0","type":"link"}